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It would be a major shock if Man United exit after three excellent results including wins against elite rivals at home & an exciting come back win at Palace in the league.
In La Liga, they have lost all four matches at the current top 4, suggesting they should struggle against an elite English side.
United are likely to be much more expansive than the first leg, though if Sevilla do net, it might make the game a more tense affair.
My Pick: Manchester Utd to Win